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What We're Reading

Each month we identify peer-reviewed articles from the medical literature as part of an ongoing effort to develop and maintain a repository of publications related to the work conducted at the Center. These monthly reviews are intended to keep us up-to-date with the evidence in the world of pragmatic trials and patient and provider engagement.

Current

Behavioral Nudges as Patient Decision Support for Medication Adherence: The ENCOURAGE Randomized Controlled Trial

Horne BD, Muhlestein JB, Lappe DL, May HT, Le VT, et al.

Am Heart J, 2022 Feb

Digital messaging to support control for type 2 diabetes (StAR2D): a multicentre randomised controlled trial

Farmer A, Bobrow K, Leon N, Williams N, Phiri E, et al.

AmBMC Public Health, 2021 Oct 21

Archives

Benefits and Harms of Hypertension and High-Normal Labels: A Randomized Experiment

Mscat DM, Morris GM, Bell K, Cvejic E, Smith J, et al. 

Circ Cardiovasc Qual Outcomes, 2021 Apr

A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor's appointment

Milkman KL, Patel MS, Gandhi L, Graci HN, Gromet DM, et al.

Proc Natl Acad Sci U S A, 2021 May 18

A Randomized Encouragement Trial to Increase Mail Order Pharmacy Use and Medication Adherence in Patients with Diabetes

Ramachandran B, Trinacty CM, Wharam JF, Duru OK, Dyer WT, et al.

J Gen Intern Med, 2021 Jan

A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor's appointment

Milkman KL, Patel MS, Gandhi L, Graci HN, Gromet DM, et al.

Proc Natl Acad Sci U S A, 2021 May 18

Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial

Wilson FP, Martin M, Yamamoto Y, Partridge C, Moreira E, et al.

BMJ, 2021 Jan 18

Electronic Decision Support for Management of CKD in Primary Care: A Pragmatic Randomized Trial

Peralta CA, Livdaudais-Toman J, Stebbins M, Lo L, Robinson A, et al.

Am J Kidney Dis. 2020 Nov 

A Randomized Encouragement Trial to Increase Mail Order Pharmacy Use and Medication Adherence in Patients with Diabetes

Ramachandran B, Trinacty CM, Wharam JF, Duru OK, Dyer WT, et al.

J Gen Intern Med. 2021 Jan

Effect of Passive Choice and Active Choice Interventions in the Electronic Health Record to Cardiologists on Statin Prescribing

Srinath Adusumalli, MD, MSc, Julie E. Westover, Douglas S. Jacoby, MD, et al. 

JAMA Cardiol. 2020 Oct

Electronic Health Record Portal Messages and Interactive Voice Response Calls to Improve Rates of Early Season Influenza Vaccination: Randomized Controlled Trial

Jessica G Wijesundara1, MPH, Mayuko Ito Fukunaga, MD, et al. 

JMIR. 2020 Sept

Weight Loss in Underserved Patients — A Cluster-Randomized Tria

Katzmarzyk PT, Martin CK, Newton RL Jr, et al.

New Eng J Med 2020 Aug

Mobile-Enhanced Peer Support for African Americans with Type 2 Diabetes: a Randomized Controlled Trial

Presley C, Agne A, Shelton T, Oster R, Cherrington A.

J Gen Intern Med. 2020 Jul

Interventions supporting long term adherence and decreasing cardiovascular events after myocardial infarction (ISLAND): pragmatic randomised controlled tria

Ivers NM, Schwalm JD, Bouck Z, McCready T, Taljaard M, Grace SL, Cunningham J, Bosiak B, Presseau J, Witteman HO, Suskin N, Wijeysundera HC, Atzema C, Bhatia RS, Natarajan M, Grimshaw JM.​

BMJ. 2020 Jun

Interventions supporting long term adherence and decreasing cardiovascular events after myocardial infarction (ISLAND): pragmatic randomised controlled tria

Ivers NM, Schwalm JD, Bouck Z, McCready T, Taljaard M, Grace SL, Cunningham J, Bosiak B, Presseau J, Witteman HO, Suskin N, Wijeysundera HC, Atzema C, Bhatia RS, Natarajan M, Grimshaw JM.

BMJ. 2020 Jun

Framing Social Comparison Feedback With Financial Incentives for Physical Activity Promotion: A Randomized Trial

Patel MS, Asch DA, Rosin R, Small DS, Bellamy SL, Hoffer K, Shuttleworth D, Hilbert V, Zhu J, Yang L, Wang X, Volpp KG.

J Phys Act Health. 2020 May

Effect of Smartphone-Enabled Health Monitoring Devices vs Regular Follow-up on Blood Pressure Control Among Patients After Myocardial Infarction: A Randomized Clinical Trial

Treskes RW, van Winden LAM, van Keulen N, van der Velde ET, Beeres SLMA, Atsma DE, Schalij MJ. 

JAMA Netw Open. 2020 Apr

Effect of Patient Portal Reminders Sent by a Health Care System on Influenza Vaccination Rates: A Randomized Clinical Trial

Szilagyi PG, Albertin C, Casillas A, Valderrama R, Duru OK, Ong MK, Vangala S, Tseng CH, Rand CM, Humiston SG, Evans S, Sloyan M, Lerner C.

JAMA Intern Med. 2020 May

Mobile Health Technology to Improve Care for Patients With Atrial Fibrillation.

Guo Y, Lane DA, Wang L, Zhang H, Wang H, Zhang W, Wen J, Xing Y, Wu F, Xia Y, Liu T, Wu F, Liang Z, Liu F, Zhao Y, Li R, Li X, Zhang L, Guo J, Burnside G, Chen Y, Lip GYH; mAF-App II Trial Investigators.

J Am Coll Cardiol. 2020 Apr

A Behavioral Economics-Based Telehealth Intervention to Improve Aspirin Adherence Following Hospitalization for Acute Coronary Syndrome

Riegel B, Stephens-Shields A, Jaskowiak-Barr A, Daus M, Kimmel SE.

Pharmacoepidemiol Drug Saf. 2020 May

The Partnership to Improve Diabetes Education Trial: a Cluster Randomized Trial Addressing Health Communication in Diabetes Care

White RO, Chakkalakal RJ, Wallston KA, Wolff K, Gregory B, Davis D, Schlundt D, Trochez KM, Barto S, Harris LA, Bian A, Schildcrout JS, Kripalani S, Rothman RL.

J Gen Intern Med. 2020 Jan

An adaptable implementation package targeting evidence-based indicators in primary care: A pragmatic cluster-randomised evaluation.

Willis TA, Collinson M, Glidewell L, Farrin AJ, Holland M, Meads D, Hulme C, Petty D, Alderson S, Hartley S, Vargas-Palacios A, Carder P, Johnson S, Foy R; ASPIRE programme team.

PLoS Med. 2020 Feb

Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays: Feasibility Randomized Controlled Trial.

Zárate-Bravo E, García-Vázquez JP, Torres-Cervantes E, Ponce G, Andrade ÁG, Valenzuela-Beltrán M, Rodríguez MD.​

JMIR Mhealth Uhealth. 2020 Mar

Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays: Feasibility Randomized Controlled Trial.

Zárate-Bravo E, García-Vázquez JP, Torres-Cervantes E, Ponce G, Andrade ÁG, Valenzuela-Beltrán M, Rodríguez MD.

JMIR Mhealth Uhealth. 2020 Mar

An adaptable implementation package targeting evidence-based indicators in primary care: A pragmatic cluster-randomised evaluation.

Willis TA, Collinson M, Glidewell L, Farrin AJ, Holland M, Meads D, Hulme C, Petty D, Alderson S, Hartley S, Vargas-Palacios A, Carder P, Johnson S, Foy R; ASPIRE programme team.

PLoS Med. 2020 Feb

Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays: Feasibility Randomized Controlled Trial.

Zárate-Bravo E, García-Vázquez JP, Torres-Cervantes E, Ponce G, Andrade ÁG, Valenzuela-Beltrán M, Rodríguez MD.​

JMIR Mhealth Uhealth. 2020 Mar

Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays: Feasibility Randomized Controlled Trial.

Zárate-Bravo E, García-Vázquez JP, Torres-Cervantes E, Ponce G, Andrade ÁG, Valenzuela-Beltrán M, Rodríguez MD.

JMIR Mhealth Uhealth. 2020 Mar

A Texting Intervention in Latino Families to Reduce ED Use: A Randomized Trial.

DeCamp LR, Godage SK, Valenzuela Araujo D, Dominguez Cortez J, Wu L, Psoter KJ, Quintanilla K, Rivera Rodríguez T, Polk S.

Pediatrics. 2020 Jan

Effectiveness of a Hospital-Based Computerized Decision Support System on Clinician Recommendations and Patient Outcomes: A Randomized Clinical Trial.

Moja L, Polo Friz H, Capobussi M, Kwag K, Banzi R, Ruggiero F, González-Lorenzo M, Liberati EG, Mangia M, Nyberg P, Kunnamo I, Cimminiello C, Vighi G, Grimshaw JM, Delgrossi G, Bonovas S.

JAMA Netw Open. 2019 Dec

Changing Results-Engage and Activate to Enhance Wellness: A Randomized Clinical Trial to Improve Cardiovascular Risk Management.

Iturralde E, Sterling SA, Uratsu CS, Mishra P, Ross TB, Grant RW.

J Am Heart Assoc. 2019 Dec

Impact of a Low-Intensity Resource Referral Intervention on Patients' Knowledge, Beliefs, and Use of Community Resources: Results from the CommunityRx Trial.

Tung EL, Abramsohn EM, Boyd K, Makelarski JA, Beiser DG, Chou C, Huang ES, Ozik J, Kaligotla C, Lindau ST.

J Gen Intern Med. 2019 Nov

Effect of Escalating Financial Incentive Rewards on Maintenance of Weight Loss: A Randomized Clinical Trial.

Yancy WS Jr, Shaw PA, Reale C, Hilbert V, Yan J, Zhu J, Troxel AB, Foster GD, Volpp KG.

JAMA Netw Open. 2019 Nov

A Systems-Level Approach to Improving Medication Adherence in Hypertensive Latinos: a Randomized Control Trial.

Schoenthaler A, de la Calle F, Pitaro M, Lum A, Chaplin W, Mogavero J, Rosal MC.

J Gen Intern Med. 2019 Oct

Effectiveness of Shared Decision-making for Diabetes Prevention: 12-Month Results from the Prediabetes Informed Decision and Education (PRIDE) Trial.

Moin T, Duru OK, Turk N, Chon JS, Frosch DL, Martin JM, Jeffers KS, Castellon-Lopez Y, Tseng CH, Norris K, Mangione CM.

J Gen Intern Med. 2019 Aug

Electronic Pill Bottles or Bidirectional Text Messaging to Improve Hypertension Medication Adherence (Way 2 Text): a Randomized Clinical Trial.

Mehta SJ, Volpp KG, Troxel AB, Day SC, Lim R, Marcus N, Norton L, Anderson S, Asch DA. 

J Gen Intern Med. 2019 Aug

Effect on Treatment Adherence of Distributing Essential Medicines at No Charge: The CLEAN Meds Randomized Clinical Trial.

Persaud N, Bedard M, Boozary AS, Glazier RH, Gomes T, Hwang SW, Jüni P, Law MR, Mamdani MM, Manns BJ, Martin D, Morgan SG, Oh PI, Pinto AD, Shah BR, Sullivan F, Umali N, Thorpe KE, Tu K, Laupacis A; Carefully Selected and Easily Accessible at No Charge Medicines (CLEAN Meds) Study Team.

JAMA Intern Med. 2019 Oct

Randomized controlled trial of OnTrack, a just-in-time adaptive intervention designed to enhance weight loss.

Forman EM, Goldstein SP, Crochiere RJ, Butryn ML, Juarascio AS, Zhang F, Foster GD.

Transl Behav Med. 2019 Nov

Home Visit Intervention Promotes Lifestyle Changes: Results of an RCT in Mexican Americans.

Vidoni ML, Lee M, Mitchell-Bennett L, Reininger BM.

Am J Prev Med. 2019 Sep

Telemonitoring and Team-Based Management of Glycemic Control on People with Type 2 Diabetes: a Cluster-Randomized Controlled Trial.

Lee JY, Chan CKY, Chua SS, Ng CJ, Paraidathathu T, Lee KKC, Lee SWH.

J Gen Intern Med. 2019 Sep

Effectiveness of Behaviorally Designed Gamification Interventions With Social Incentives for Increasing Physical Activity Among Overweight and Obese Adults Across the United States: The STEP UP Randomized Clinical Trial.

Patel MS, Small DS, Harrison JD, Fortunato MP, Oon AL, Rareshide CAL, Reh G, Szwartz G, Guszcza J, Steier D, Kalra P, Hilbert V.

JAMA Intern Med. 2019 Sep

A Toolbox Approach to Obesity Treatment in Urban Safety-Net Primary Care Clinics: a Pragmatic Clinical Trial.

Saxon DR, Chaussee EL, Juarez-Colunga E, Tsai AG, Iwamoto SJ, Speer RB, Heyn H, Kealey EH, Bessesen DH.

J Gen Intern Med. 2019 Aug

Effects of Mobile Text Messaging on Glycemic Control in Patients With Coronary Heart Disease and Diabetes Mellitus: A Randomized Clinical Trial.

Huo X, Krumholz HM, Bai X, Spatz ES, Ding Q, Horak P, Zhao W, Gong Q, Zhang H, Yan X, Sun Y, Liu J, Wu X, Guan W, Wang X, Li J, Li X, Spertus JA, Masoudi FA, Zheng X.

Circ Cardiovasc Qual Outcomes. 2019 Sep

Effect of Different Financial Incentive Structures on Promoting Physical Activity Among Adults: A Randomized Clinical Trial.

Bachireddy C, Joung A, John LK, Gino F, Tuckfield B, Foschini L, Milkman KL.

JAMA Netw Open. 2019 Aug 

​

Effectiveness of Shared Decision-making for Diabetes Prevention: 12-Month Results from the Prediabetes Informed Decision and Education (PRIDE) Trial.

Moin T, Duru OK, Turk N, Chon JS, Frosch DL, Martin JM, Jeffers KS, Castellon-Lopez Y, Tseng CH, Norris K, Mangione CM.

J Gen Intern Med. 2019 Aug

Electronic Pill Bottles or Bidirectional Text Messaging to Improve Hypertension Medication Adherence (Way 2 Text): a Randomized Clinical Trial.

Mehta SJ, Volpp KG, Troxel AB, Day SC, Lim R, Marcus N, Norton L, Anderson S, Asch DA.

J Gen Intern Med. 2019 Aug

Efficacy of a self-management education programme on patients with type 2 diabetes in primary care: A randomised controlled trial.

Gamboa Moreno E, Mateo-Abad M, Ochoa de Retana García L, Vrotsou K, Del Campo Pena E, Sánchez Perez Á, Martínez Carazo C, Arbonies Ortiz JC, Rúa Portu MÁ, Piñera Elorriaga K, Zenarutzabeitia Pikatza A, Urquiza Bengoa MN, Méndez Sanpedro T, Oses Portu A, Aguirre Sorondo MB, Rotaeche Del Campo R; Osakidetza Active Patient Research Group.

Prim Care Diabetes. 2019 Apr

Effect of enhancing audit and feedback on uptake of childhood pneumonia treatment policy in hospitals that are part of a clinical network: a cluster randomized trial.

Ayieko P, Irimu G, Ogero M, Mwaniki P, Malla L, Julius T, Chepkirui M, Mbevi G, Oliwa J, Agweyu A, Akech S, Were F, English M; Clinical Information Network Authors.

Implement Sci. 2019 Mar

Effectiveness of a Bundled Intervention Including Adjunctive Corticosteroids on Outcomes of Hospitalized Patients With Community-Acquired Pneumonia: A Stepped-Wedge Randomized Clinical Trial.

Lloyd M, Karahalios A, Janus E, Skinner EH, Haines T, De Silva A, Lowe S, Shackell M, Ko S, Desmond L, Karunajeewa H; Improving Evidence-Based Treatment Gaps and Outcomes in Community-Acquired Pneumonia (IMPROVE-GAP) Implementation Team at Western Health.

JAMA Intern Med. 2019 July 

Use of financial incentives and text message feedback to increase healthy food purchases in a grocery store cash back program: a randomized controlled trial.

Gopalan A, Shaw PA, Lim R, Paramanund J, Patel D, Zhu J, Volpp KG, Buttenheim AM.

BMC Public Health. 2019 May 

Patient-centered communication and shared decision making to reduce HbA1c levels of patients with poorly controlled type 2 diabetes mellitus - results of the cluster-randomized controlled DEBATE trial.

Wollny A, Altiner A, Daubmann A, Drewelow E, Helbig C, Löscher S, Pentzek M, Santos S, Wegscheider K, Wilm S, Löffler C.

BMC Fam Pract. 2019 June

Using Adherence-Contingent Rebates on Chronic Disease Treatment Costs to Promote Medication Adherence: Results from a Randomized Controlled Trial.

Bilger M, Wong TT, Lee JY, Howard KL, Bundoc FG, Lamoureux EL, Finkelstein EA.

Appl Health Econ Health Policy. 2019 Jul

The Effect of a Screening and Treatment Program for the Prevention of Fractures in Older Women: A Randomized Pragmatic Trial.

Merlijn T, Swart KM, van Schoor NM, Heymans MW, van der Zwaard BC, van der Heijden AA, Rutters F, Lips P, van der Horst HE, Niemeijer C, Netelenbos JC, Elders PJ.

J Bone Miner Res. 2019 Jun

Effect of a Self-management Support Intervention on Asthma Outcomes in Older Adults: The SAMBA Study Randomized Clinical Trial.

Federman AD, O'Conor R, Mindlis I, Hoy-Rosas J, Hauser D, Lurio J, Shroff N, Lopez R, Erblich J, Wolf MS, Wisnivesky JP.

JAMA Intern Med. 2019 June 

What is the impact of increasing the prominence of calorie labelling? A stepped wedge randomised controlled pilot trial in worksite cafeterias.

Vasiljevic M, Fuller G, Pilling M, Hollands GJ, Pechey R, Jebb SA, Marteau TM.

Appetite. 2019 Oct (Epub 2019 May)

Effect of Text Messaging on Risk Factor Management in Patients With Coronary Heart Disease: The CHAT Randomized Trial.

Zheng X , Spatz ES , Bai X , Huo X , Ding Q , Horak P , Wu X, Guan W, Chow CK, Yan X , Sun Y , Wang X , Zhang H , Liu J, Li J, Li X , Spertus JA, Masoudi FA, Krumholz HM.

Circ Car Qual Out. 2019 April

Outcomes From a Sequential Multiple Assignment Randomized Trial of Weight Loss Strategies for African American Adolescents With Obesity.

Naar S, Ellis D, Idalski Carcone A, Jacques-Tiura AJ, Cunningham P, Templin T, Hartlieb KB, Jen KC.

Ann Behav Med. 2019 April

Short Message Service Text Message Support for Weight Loss in Patients With Prediabetes: Pragmatic Trial.

Fischer HH, Durfee MJ, Raghunath SG, Ritchie ND.

JMIR Diabetes. 2019 April

Effect of an Incentive Spirometer Patient Reminder After Coronary Artery Bypass Grafting: A Randomized Clinical Trial.

Eltorai AEM, Baird GL, Eltorai AS, Healey TT, Agarwal S, Ventetuolo CE, Martin TJ, Chen J, Kazemi L, Keable CA, Diaz E, Pangborn J, Fox J, Connors K, Sellke FW, Elias JA, Daniels AH.

JAMA Surg. 2019 April

Using a smartphone app in changing cardiovascular risk factors: A randomized controlled trial (EVIDENT II study).

Gonzalez-Sanchez J, Recio-Rodriguez JI, Fernandez-delRio A, Sanchez-Perez A, Magdalena-Belio JF, Gomez-Marcos MA, Garcia-Ortiz L; On behalf the EVIDENT Investigators group.

Int J Med Inform. 2019 May

Effect of Text Messaging on Risk Factor Management in Patients With Coronary Heart Disease: The CHAT Randomized Trial.

Zheng X , Spatz ES , Bai X , Huo X , Ding Q , Horak P , Wu X, Guan W, Chow CK, Yan X , Sun Y , Wang X , Zhang H , Liu J, Li J, Li X , Spertus JA, Masoudi FA, Krumholz HM.

Circ Car Qual Out. 2019 April

Outcomes From a Sequential Multiple Assignment Randomized Trial of Weight Loss Strategies for African American Adolescents With Obesity.

Naar S, Ellis D, Idalski Carcone A, Jacques-Tiura AJ, Cunningham P, Templin T, Hartlieb KB, Jen KC.

Ann Behav Med. 2019 April

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