Publications

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Using data-driven approaches to classify and predict healthcare spending in patients with gout using urate-lowering therapy

Lauffenburger JC, Lu Z, Mahesri M, Kim E, Tong A, Kim SC.

 

Arthritis Care Res (Hoboken) 2022 Aug 30

 
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Frequency of Quarterly Self-reported Health-Related Social Needs Among Older Adults, 2020

Haff N, Choudhry NK, Bhatkhande G, Li Y, Drzayich Antol D, Renda A, Lauffenburger JC.

 

JAMA Netw Open. 2022 Jun 30

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Factors Associated with Lower Preoperative Quality of Life in Patients with Chronic Limb Threatening Ischemia in the BEST-CLI Trial

Powell RJ, Choudhry NK, Conte M, Cziraky M, Giles K, Hamza T, Menard M, Rosenfeld K, Rowe V, Siracuse J, Strong M, Van Over M, Villarreal M, White C, Farber A

 

J Vasc Surg. 2022 Jun 14

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Prescribing decision making by medical residents on night shifts: A qualitative study

Lauffenburger JC, Coll MD, Kim E, Robertson T, Oran R, Haff N, Hanken K, Avorn J, Choudhry NK

 

Med Educ. 2022 May 25

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Leveraging Social Networks for the Assessment and Management of Neurological Patients

Dhand A, Podury A, Choudhry N, Narayanan S, Shin M, Mehl MR

 

Semin Neurol. 2022 Apr

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A novel modality for real-time measurement of provider happiness

Carlile N, Tantillo S, Brown M, Bates DW, Choudhry NK

 

JAMIA Open. 2022 Feb 24

 
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Association Between Primary Care Payment Model and Telemedicine Use for Medicare Advantage Enrollees During the COVID-19 Pandemic

Powers BW, Drzayich Antol D, Zhao Y, Haugh GS, Roman O, Shrank WH, Choudhry NK.​

JAMA Health Forum 2021 Jul

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Preferences for mHealth Technology and Text Messaging Communication in Patients With Type 2 Diabetes: Qualitative Interview Study

Lauffenburger JC, Barlev RA, Sears ES, Keller PA, McDonnel ME, Yom-Tov E, Fontanet CP, Hanken K, Haff N, Choudhry NK​

J Med Internet Res 2021 Jun

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Virtual Optimization of Guideline-Directed Medical Therapy in Hospitalized Patients with Heart Failure with Reduced Ejection Fraction: the IMPLEMENT-HF Pilot Study

Bhatt AS, Varshney AS, Nekoui M, Moscone A, Cunningham JW, Jering KS, Patel PN, Sinnenberg LE, Bernier TD, Buckley LF, Cook B, Dempsey J, Kelly J, Knowles DM, Lupi K, Malloy R, Matta LS, Rhoten MN, Sharma K, Snyder CA, Ting C, McElrath EE, Amato MG, Alobaidly M, Ulbricht CE, Choudhry NK, Adler DS, Vaduganathan M. 

 

Eur J Heart Fail. 2021 Mar

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Rationale and design of the Novel Uses of adaptive Designs to Guide provider Engagement in Electronic Health Records (NUDGE-EHR) pragmatic adaptive randomized trial: a trial protocol

Lauffenburger JC, Isaac T, Trippa L, Keller P, Robertson T, Glynn RJ, Sequist TD, Kim DH, Fontanet CP, Castonguay EWB, Haff N, Barlev Ra, Mahesri M, Gopalakrishnan C, and Choudhry NK.

Implementation Science 2021 Jan

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Use of Data-Driven Methods to Predict Long-term Patterns of Health Care Spending for Medicare Patients.

Lauffenburger JC, Mahesri M, Choudhry NK.

JAMA Netw Open. 2020 Oct

 
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Comparison of a new three-item self-reported measure of adherence to medication with pharmacy claims data in patients with cardiometabolic disease. 

Lauffenburger JC, Fontanet CP, Isaac T, Gopalakrishnan C, Sequist TD, Gagne JJ, Jackevicius CA, Fischer MA, Solomon DH, Choudhry NK. 

Am Heart J 2020 Jun

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Impact of a Copayment Reduction Intervention on Medication Persistence and Cardiovascular Events in Hospitals With and Without Prior Medication Financial Assistance Programs.

Doll JA, Kaltenbach LA, Anstrom KJ, Cannon CP, Henry TD, Fonarow GC, Choudhry NK, Fonseca E, Bhalla N, Eudicone JM, Peterson ED, Wang TY.

J Am Heart Assoc. 2020 Apr

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Agreement and Accuracy of Medication Persistence Identified by Patient Self-report vs Pharmacy Fill: A Secondary Analysis of the Cluster Randomized ARTEMIS Trial.

Fanaroff AC, Peterson ED, Kaltenbach LA, Cannon CP, Choudhry NK, Henry TD, Anstrom KJ, Cohen DJ, Fonseca E, Khan ND, Fonarow GC, Wang TY. 

JAMA Cardiol. 2020 Mar

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Prevalence and Impact of Having Multiple Barriers to Medication Adherence in Non-adherent Patients with Poorly-controlled Cardiometabolic Disease.

Lauffenburger JC, Isaac T, Bhattacharya R, Sequist TD, Gopalakrishnan C, Choudhry NK.

Am. J. Cardiol. 2020 Feb

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Association of Potentially Modifiable Diabetes Care Factors With Glycemic Control in Patients With Insulin-Treated Type 2 Diabetes.

Lauffenburger JC, Lewey J, Jan S, Lee J, Ghazinouri R, Choudhry NK.

JAMA Netw Open. 2020 Jan

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Association of a P2Y12 Inhibitor Copayment Reduction Intervention With Persistence and Adherence With Other Secondary Prevention Medications: A Post Hoc Analysis of the ARTEMIS Cluster-Randomized Clinical Trial.

Fanaroff AC, Peterson ED, Kaltenbach LA, Cannon CP, Choudhry NK, Henry TD, Anstrom KJ, Cohen DJ, Fonseca E, Khan ND, Fonarow GC, Wang TY. 

JAMA Cardiol. 2019 Nov 

 
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Association between physician adoption of a new oral anti-diabetic medication and Medicare and Medicaid drug spending.

Metes ID, Xue L, Chang C-CH, Huskamp HA, Gellad WF, Lo-Ciganic W-H, Choudhry NK, Richards-Shubik S, Guclu H, Donohue JM.

BMC Health Serv. Res 2019 Oct

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A concept‐wide association study to identify potential risk factors for nonadherence among prevalent users of antihypertensives.

Singh K, Choudhry NK, Krumme AA, McKay C, McElwee NE, Kimura J, Franklin JM. 

Pharmacoepidemiol Drug Saf. 2019 July

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A bronchial-airway gene-expression classifier to improve the diagnosis of lung cancer: clinical outcomes and cost-effectiveness analysis. 

D’Andrea E, Choudhry NK, Raby B, Weinhouse G, Najafzadeh M. 

Int J Cancer. 2019 April

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General Population vs. Patient Preferences in Anticoagulant Therapy: A Discrete Choice Experiment.

Najafzadeh M, Schneeweiss S, Choudhry NK, Avorn J, Gagne JJ.

Patient. 2019 April

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Effect of Targeted Insulin Adherence Interventions for Glycemic Control With Predictive Analytics Among Patients With Type 2 Diabetes: The TARGIT-Diabetes Randomized Clinical Trial. 

Lauffenburger JC, Lewey J, Jan S, Makanji S, Ferro CA, Krumme AA, Lee J, Ghazinouri R, Haff N, Choudhry NK. 

JAMA Network Open 2019 March 15

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Utilization Patterns of Oral Disease-Modifying Drugs in Commercially Insured Patients with Multiple Sclerosis.

Desai RJ, Mahesri M, Gagne JJ, Hurley E, Tong A, Chitnis T, Minden S, Spettell CM, Matlin OS, Shrank WH, Choudhry NK.

Journal of Managed Care and Specialty Pharmacy 2019 January 

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Quantifying Social Reinforcement Among Family Members on Adherence to Medications for Chronic Conditions: a US-Based Retrospective Cohort Study.

Lauffenburger JC, Khan NF, Brill G, Choudhry NK. 

Journal of General Internal Medicine 2018 November 07

 
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Impact of High Deductible Health Plans on Cardiovascular Medication Adherence and Health Disparities.

Lewey J, Gagne JJ, Franklin J, Lauffenburger JC, Brill G, Choudhry NK.

Circulation: Quality and Outcomes 2018 November

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Time to Filling of New Prescriptions for Chronic Disease Medications Among a Cohort of Elderly Patients in the USA.

Franklin JM, Mahesri M, Krumme AA, Barberio J, Fischer MA, Brill G, McKay C, Black H, Choudhry NK. 

Journal of General Internal Medicine 2018 November

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Using Previous Medication Adherence to Predict Future Adherence.

Kumamaru H, Lee MP, Choudhry NK, Dong Y-H, Krumme AA, Khan N, Brill G, Kohsaka S, Miyata H, Schneeweiss S, Gagne JJ. 

Journal of Managed Care & Specialty Pharmacy 2018 October

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The Promise and Pitfalls of Pragmatic Clinical Trials for Improving Health Care Quality.

Haff N, Choudhry NK.

JAMA Network Open 2018 October 26

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Impact of a metoprolol ER shortage on post-myocardial infarction beta-blocker utilization, adherence, and re-hospitalization.

Bykov K, Gagne JJ, Wang B, Choudhry NK. 

Circulation: Cardiovascular Quality and Outcomes 2018 October

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Letters designed with behavioural science increase influenza vaccination in Medicare beneficiaries.

Yokum D, Lauffenburger J, Ghazinouri R, Choudhry NK. 

Nature Human Behaviour 2018 October 01

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Effect of a Remotely Delivered Tailored Multicomponent Approach to Enhance Medication Taking for Patients With Hyperlipidemia, Hypertension, and Diabetes: The STIC2IT Cluster Randomized Clinical Trial.

Choudhry NK, Isaac T, Lauffenburger JC, Gopalakrishnan C, Lee M, Vachon A, Iliadis TL, Hollands W, Elman S, Kraft JM, Naseem S, Doheny S, Lee J, Barberio J, Patel L, Khan NF, Gagne JJ, Jackevicius CA, Fischer MA, Solomon DH, Sequist TD.

JAMA Internal Medicine. 2018 September

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A Call for a Systems-Thinking Approach to Medication Adherence: Stop Blaming the Patient.

Lauffenburger JC, Choudhry NK.

JAMA Intern Med. 2018 July 01

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Defining Exposure in Observational Studies Comparing Outcomes of Treatment Discontinuation.

Krumme AA, Glynn RJ, Schneeweiss S, Choudhry NK, Tong AY, Gagne JJ.

Circulation: Cardiovasc Qual Outcomes. 2018 July 10

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Association of a smartphone application with medication adherence and blood pressure control - The MedISAFE-BP randomized clinical trial.

Morawski K, Ghazinouri R, Krumme A, Lauffenburger JC, Lu Z, Durfee E, Oley L, Lee J, Mohta N, Haff N, Juusola JL, Choudhry NK.

JAMA Intern Med. 2018 June

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Predicting Adherence to Chronic Disease Medications in Patients with Long-term Initial Medication Fills Using Indicators of Clinical Events and Health Behaviors.

Lauffenburger JC, Franklin JM Krumme, AA, Shrank WH, Matlin OS, Spettell CM, Brill G, Choudhry NK.

J Manag Care Spec Pharm. 2018 May

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The relative benefits of claims and electronic health record data for predicting medication adherence trajectory.

Franklin JM, Gopalakrishnan C, Krumme AA, Singh K, Rogers JR, Kimura J, McKay C, McElwee NE, Choudhry NK.

Am Heart J. 2018 March

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Simulation for predicting effectiveness and safety of new cardiovascular drugs in routine care populations.

Najafzadeh M, Schneeweiss S, Choudhry NK, Wang SV, Gagne JJ.

Clin Pharmacol Ther. 2018 February 09

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Medication synchronization programs improve adherence to cardiovascular medications and health care use.

Krumme AA, Glynn RJ, Schneeweiss S, Gagne JJ, Dougherty JS, Brill G, Choudhry NK.

Health Aff. 2018 January

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Study protocol for the dabigatran, apixaban, rivaroxaban, edoxaban, warfarin comparative effectiveness research study.

Krumme AA, Pawar A, Schneeweiss S, Glynn RJ, Choudhry NK, Kulldorff M, Ortiz AS, Avorn J, Gagne JJ.

J Comp Eff Res. 2017 December 21

 
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Exploring attributes of high-value primary care.

Simon M, Choudhry NK, Frankfort J, Margolius D, Murphy J, Paita L, Wang T, Milstein A.

Ann Fam Med. 2017 November

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Patterns of opioid initiation at first visits for pain in United States primary care settings.

Mundkur ML, Rough K, Huybrechts KF, Levin R, Gagne JJ, Desai RJ, Patorno E, Choudhry NK, Bateman BT.

Pharmacoepidemiol Drug Saf. 2017 October 02

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Targeted Adherence intervention to Reach Glycemic control with Insulin Therapy for patients with Diabetes (TARGIT-Diabetes): rationale and design of a pragmatic randomised clinical trial.

Lewey J, Wei W, Lauffenburger JC, Makanji S, Chant A, DiGeronimo J, Nanchanatt G, Jan S, Choudhry NK.

BMJ Open. 2017 October 30

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The impact of a retail prescription synchronization program on medication adherence.

Girdish C, Shrank W, Freytag S, Chen D, Gebhard D, Bunton A, Choudhry N, Polinski J.

J Am Pharm Assoc. 2017 September-October

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Rationale and design of the ENhancing outcomes through Goal Assessment and Generating Engagement in Diabetes Mellitus (ENGAGE-DM) pragmatic trial.

Lauffenburger JC, Lewey J, Jan S, Nanchanatt G, Makanji S, Ferro CA, Sheehan J, Wittbrodt E, Morawski K, Lee J, Ghazinouri R, Choudhry NK.

Contemp Clin Trials. 2017 August

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Cost-effectiveness of palbociclib in hormone receptor-positive advanced breast cancer.

Mamiya H, Tahara RK, Tolaney SM, Choudhry NK, Najafzadeh M.

Ann Oncol. 2017 August 01

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Hypertension management in Brazil: usual practice in primary care - a meta-analysis.

Picon RV, Dias-da-Costa JS, Fuchs FD, Olinto MTA, Choudhry NK, Fuchs SC.

Int J Hypertens. 2017 July 02

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A shared decision-making intervention to guide opioid prescribing after cesarean delivery.

Prabhu M, McQuaid-Hanson E, Hopp S, Burns SM, Leffert LR, Landau R, Lauffenburger JC, Choudhry NK, Kaimal A, Bateman BT.

Obstet Gynecol. 2017 July

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Effect of reminder devices on medication adherence: the REMIND randomized clinical trial.

Choudhry NK, Krumme AA, Ercole PM, Girdish C, Tong A, Khan N, Brennan TA, Matlin OS, Shrank WH, Franklin JM.

JAMA Intern Med. 2017 May

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Patterns and predictors of persistent opioid use following hip or knee arthroplasty.

Kim SC, Choudhry N, Franklin JM, Bykov K, Eikermann M, Lii J, Fischer MA, Bateman BT.

Osteoarthritis Cartilage. 2017 April 19

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Rationale and design of the Medication adherence Improvement Support App For Engagement - Blood Pressure (MedISAFE-BP) trial.

Morawski K, Ghazinouri R, Krumme A, McDonough J, Durfee E, Oley L, Mohta N, Juusola J, Choudhry NK.

Am Heart J. 2017 April

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Predicting 1-year statin adherence among prevalent users: a retrospective cohort study.

Krumme AA, Franklin JM, Isaman DL, Matlin OS, Tong AY, Spettell CM, Brennan TA, Shrank WH, Choudhry NK.

J Manag Care Spec Pharm. 2017 April

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Clinical outcomes of concomitant use of warfarin and selective serotonin reuptake inhibitors: a multidatabase observational cohort study.

Dong YH, Bykov K, Choudhry NK, Donneyong MM, Huybrechts KF, Levin R, Schneeweiss S, Gagne JJ

J Clin Psychopharmacol. 2017 April

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Impact of hospitalization on medication adherence estimation in claims data.

Dong Y-H, Choudhry NK, Krumme A, Lee MP, Wu LC, Lai MS, Gagne JJ.

J Clin Pharm Ther. 2017 March 29

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Association between patient-centered medical homes and adherence to chronic disease medications: a cohort study.

Lauffenburger JC, Shrank WH, Bitton A, Franklin JM, Glynn RJ, Krumme AA, Matlin OS, Pezalla EJ, Spetell CM, Brill G, Choudhry NK.

Ann Intern Med. 2017 January 17

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Longitudinal patterns of spending enhance the ability to predict costly patients: a novel approach to identify patients for cost containment.

Lauffenburger JC, Franklin JM, Krumme AA, Shrank WH, Brennan TA, Matlin OS, Spettell CM, Brill G, Choudhry NK.

Med Care. 2017 January

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Impact of an interaction between clopidogrel and selective serotonin reuptake inhibitors.

Bykov K, Schneeweiss S, Donneyong MM, Dong YH, Choudhry NK, Gagne JJ.

Am J Cardiol. 2016 November 16

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Can purchasing information be used to predict adherence to cardiovascular medications? An analysis of linked retail pharmacy and insurance claims data.

Krumme AA, Sanfelix-Gimeno G, Franklin JM, Isaman DL, Mahesri M, Matlin OS, Shrank WH, Brennan TA, Brill G, Choudhry NK.

BMJ Open. 2016 November 09

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Switching generic antiepileptic drug manufacturer not linked to seizures: A case-crossover study.

Kesselheim AS, Bykov K, Gagne JJ, Wang SV, Choudhry NK.

Neurology. 2016 October 25

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Strength of evidence for labeled dosing recommendations in renal impairment.

Gagne JJ, Khan NF, Raj TS, Patel LR, Choudhry NK.

Clin Trials. 2016 October 24

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Economic value of pharmacist-led medication reconciliation for reducing medication errors after hospital discharge.

Najafzadeh M, Schnipper JL, Shrank WH, Kymes S, Brennan TA, Choudhry NK.

Am J Manag Care. 2016 October 14

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Rationale and design of the Study of a Tele-pharmacy Intervention for Chronic diseases to Improve Treatment adherence (STIC2IT): A cluster-randomized pragmatic trial.

Choudhry NK, Isaac T, Lauffenburger JC, Gopalakrishnan C, Khan NF, Lee M, Vachon A, Iliadis TL, Hollands W, Doheny S, Elman S, Kraft JM, Naseem S, Gagne JJ, Jackevicius CA, Fischer MA, Solomon DH, Sequist TD.

Am Heart J. 2016 October

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Persistent opioid use following cesarean delivery: patterns and predictors among opioid-naive women.

Bateman BT, Franklin JM, Bykov K, Avorn J, Shrank WH, Brennan TA, Landon JE, Rathmell JP, Huybrechts KF, Fischer MA, Choudhry NK.

Am J Obstet Gynecol. 2016 September

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Potentially disruptive life events: what are the immediate impacts on chronic disease management? A case-crossover analysis.

Lauffenburger JC, Gagne JJ, Song Z, Brill G, Choudhry NK.

BMJ Open. 2016 August 04

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Impact of Massachusetts health reform on enrollment length and health care utilization in the unsubsidized individual market.

Garabedian LF, Ross-Degnan D, Soumerai SB, Choudhry NK, Brown JS.

Health Serv Res. 2016 July 25

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Who were the early adopters of dabigatran?: an application of group-based trajectory models.

Lo-Ciganic WH, Gellad WF, Huskamp HA, Choudhry NK, Chang CC, Zhang R, Jones BL, Guclu H, Richards-Shubik S, Donohue JM.

Med Care. 2016 July

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Prevalence, effectiveness, and characteristics of pharmacy-based medication synchronization programs.

Krumme AA, Isaman DL, Stolpe SF, Dougherty S, Choudhry NK.

Am J Manag Care. 2016 March

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Brief Report: Intensification to triple therapy after treatment with nonbiologic disease-modifying antirheumatic drugs for rheumatoid arthritis in the United States from 2009 to 2014.

Sparks JA, Krumme AA, Shrank WH, Matlin OS, Brill G, Pezalla EJ, Choudhry NK, Solomon DH.

Arthritis Rheumatol. 2016 February 11

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Medicaid prescription limits: policy trends and comparative impact on utilization.

Lieberman DA, Polinski JM, Choudhry NK, Avorn J, Fischer MA.

BMC Health Serv Res. 2016 January 15

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Text messaging and patient engagement in an increasingly mobile world.

Lauffenburger JC, Choudhry NK.

Circulation. 2016 January 14

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Prospective benefit-risk monitoring of new drugs for rapid assessment of net favorability in electronic health care data.

Gagne JJ, Bykov K, Najafzadeh M, Choudhry NK, Martin DP, Kahler KH, Rogers JR, Schneeweiss S.

Value Health. 2015 December