Forgetfulness is a major contributor to nonadherence to chronic disease medications and could be addressed with medication reminder devices. To address this barrier, the Randomized Evaluation to Measure Improvements in Nonadherence from Low-Cost Devices (REMIND) trial (n=53,480) was conducted in partnership with CVS Caremark and sought to compare the effect of 3 low-cost reminder devices on medication adherence. There was no statistically significant difference in the odds of optimal adherence between the control and any of the devices.
Principal Investigator: Niteesh Choudhry, MD, PhD
Effect of reminder devices on medication adherence: the REMIND randomized clinical trial.
Choudhry NK, Krumme AA, Ercole PM, Girdish C, Tong A, Khan N, Brennan TA, Matlin OS, Shrank WH, Franklin JM.
JAMA Intern Med
Rationale and design of the Randomized Evaluation to Measure Improvements in Non-adherence from Low-Cost Devices (REMIND) trial.
Choudhry NK, Krumme AA, Ercole PM, Girdish C, Isaman DL, Matlin OS, Brennan TA, Shrank WH, Franklin JM.
Contemp Clin Trials