STIC2IT
Disagreement between pharmacy claims and direct interview to identify patients with non-adherence to chronic cardiometabolic medications
Haff N, Choudhry NK, Isaac T, Bhatkhande G, Jackevicius CA, Fischer MA, Solomon DH, Sequist TD, Lauffenburger JC
Am Heart J
2023 February
Comparison of measures of medication adherence from pharmacy dispensing and insurer claims data
Fontanet CP, Choudhry NK, Isaac T, Sequist TD, Gopalakrishnan C, Gagne JJ, Jackevicius CA, Fischer MA, Solomon DH, Lauffenburger JC
Health Serv Res
2022 June
Comparison of a new three-item self-reported measure of adherence to medication with pharmacy claims data in patients with cardiometabolic disease.
Lauffenburger JC, Fontanet CP, Isaac T, Gopalakrishnan C, Sequist TD, Gagne JJ, Jackevicius CA, Fischer MA, Solomon DH, Choudhry NK.
Am Heart J
2020 June
Prevalence and Impact of Having Multiple Barriers to Medication Adherence in Non-adherent Patients with Poorly-controlled Cardiometabolic Disease.
Lauffenburger JC, Isaac T, Bhattacharya R, Sequist TD, Gopalakrishnan C, Choudhry NK
Am J Cardiol
2020 February
Effect of a Remotely Delivered Tailored Multicomponent Approach to Enhance Medication Taking for Patients With Hyperlipidemia, Hypertension, and Diabetes: The STIC2IT Cluster Randomized Clinical Trial.
Choudhry NK, Isaac T, Lauffenburger JC, Gopalakrishnan C, Lee M, Vachon A, Iliadis TL, Hollands W, Elman S, Kraft JM, Naseem S, Doheny S, Lee J, Barberio J, Patel L, Khan NF, Gagne JJ, Jackevicius CA, Fischer MA, Solomon DH, Sequist TD.
JAMA Internal Medicine
2018 September
Rationale and design of the Study of a Tele-pharmacy Intervention for Chronic diseases to Improve Treatment adherence (STIC2IT): A cluster-randomized pragmatic trial.
Choudhry NK, Isaac T, Lauffenburger JC, Gopalakrishnan C, Khan NF, Lee M, Vachon A, Iliadis TL, Hollands W, Doheny S, Elman S, Kraft JM, Naseem S, Gagne JJ, Jackevicius CA, Fischer MA, Solomon DH, Sequist TD.
Am Heart J
2016 October
The efficacy of interventions to improve adherence may be increased by targeting interventions to patients that demonstrate both poor adherence and poor disease control, tailoring interventions to individual patient needs, and touching larger and more representative patient populations and care settings. The Study of a Tele-pharmacy Intervention for Chronic diseases to Improve Treatment adherence (STIC2IT) trial was conducted in partnership with Atrius and enrolled 4,078 patients to evaluate the impact of a novel tele-pharmacist intervention on adherence to maintenance medications. The intervention improved adherence, reduced the likelihood of emergency department visits and reduced cholesterol levels although did not influence other measures of resource utilization or disease control.
ClinicalTrials.gov: NCT02512276
Co-Principal Investigators: Niteesh Choudhry, MD, PhD and Thomas Sequist, MD, MPH